{"id":917,"date":"2013-12-16T10:42:59","date_gmt":"2013-12-16T02:42:59","guid":{"rendered":"http:\/\/sex.ncu.edu.tw\/blognews\/?p=917"},"modified":"2014-09-26T11:48:01","modified_gmt":"2014-09-26T03:48:01","slug":"%e6%88%91%e5%80%91%e7%a9%b6%e7%ab%9f%e7%9f%a5%e9%81%93%e4%ba%86%e4%bb%80%e9%ba%bd%ef%bc%9f-%e2%80%95%e2%80%95%e9%97%9c%e6%96%bc%e4%ba%ba%e9%a1%9e%e5%9f%ba%e5%9b%a0%e7%b5%84%e5%ba%8f%e5%88%97","status":"publish","type":"post","link":"https:\/\/sex.ncu.edu.tw\/blognews\/?p=917","title":{"rendered":"\u6211\u5011\u7a76\u7adf\u77e5\u9053\u4e86\u4ec0\u9ebd\uff1f \u2015\u2015\u95dc\u65bc”\u4eba\u985e\u57fa\u56e0\u7d44\u5e8f\u5217”\u6700\u65b0\u7814\u7a76\u5831\u544a\u7684\u7d9c\u8ff0"},"content":{"rendered":"
\"2\u670815\u65e5\u51fa\u7248\u7684\u300a\u81ea\u7136\u300b\u96dc\u8a8c\"

2\u670815\u65e5\u51fa\u7248\u7684\u300a\u81ea\u7136\u300b\u96dc\u8a8c<\/p><\/div>\n

\u30102001.02.23 \u00a0\u53f2\u5b63\u937e\u7de8\u8b6f\u3011<\/p>\n

\u3000”\u4eba\u985e\u57fa\u56e0\u7d44\u5e8f\u5217”\u7684\u7834\u8b6f\u662f\u79d1\u5b78\u53f2\u4e0a\u7684\u91cc\u7a0b\u7891\uff0c\u5176\u610f\u7fa9\u4e4b\u91cd\u5927\u53ef\u4ee5\u8207\u4eba\u985e\u767b\u4e0a\u6708\u7403\u3001\u5206\u88c2\u539f\u5b50\u3001\u6216\u662f\u4eba\u985e\u767c\u660e\u8f2a\u5b50\u76f8\u63d0\u4e26\u8ad6\u3002\u9019\u9805\u7814\u7a76\u5be6\u969b\u4e0a\u5728\u5169\u500b\u9663\u71df\u7684\u7af6\u722d\u4e2d\u5c55\u958b\uff0c\u4e00\u500b\u662f\u516c\u5171\u57fa\u91d1\u652f\u63f4\u7684\u4eba\u985e\u57fa\u56e0\u7d44\u8a08\u5283\uff08Human Genome Project\uff0cHGP\uff09\uff0c\u9084\u6709\u4e00\u500b\u662f\u7f8e\u570b\u585e\u840a\u62c9\u907a\u50b3\u4fe1\u606f\u516c\u53f8\uff08The American company Celera Genomics\uff09\uff0c\u5169\u8005\u5404\u81ea\u7368\u7acb\uff0c\u65b9\u6cd5\u4e0d\u540c\uff0c\u4f46\u7372\u5f97\u4e86\u5927\u81f4\u76f8\u7576\u7684\u7d50\u679c*\u3002<\/p>\n

\u3000\u30002\u670815\u65e5\u82f1\u570b\u300a\u81ea\u7136\u300b\u96dc\u8a8c\u767c\u8868\u4e86HGP\u7684\u8349\u6848\u5831\u544a\uff0c\u4e26\u65bc12\u65e5\u5728\u4e92\u806f\u7db2\u4e0a\uff08http:\/\/www.nature.com\/nature<\/a>\uff09\u516c\u4f48\u4e86\u6240\u6709\u7814\u7a76\u7d50\u679c\u30022\u670816\u65e5\uff0c\u7f8e\u570b\u300a\u79d1\u5b78\u300b\u96dc\u8a8c\u767c\u8868\u4e86\u585e\u840a\u62c9\u516c\u53f8\u7684\u7814\u7a76\u5831\u544a\uff0c\u4e5f\u5728\u7db2\u4e0a\uff08http:\/\/www.sciencemag.org\/<\/a>\uff09\u516c\u4f48\u4e86\u4e3b\u8981\u6210\u679c\u3002<\/p>\n

\u901a\u904e\u5a92\u9ad4\u9023\u7bc7\u7d2f\u7258\u7684\u5831\u9053\uff0c\u6574\u500b\u4e16\u754c\u90fd\u7232”\u751f\u547d\u5929\u66f8”\u7684\u7834\u8b6f\u800c\u9a5a\u6b4e\uff0c\u4f46\u6211\u5011\u5927\u591a\u6578\u4eba\u4e26\u4e0d\u5b8c\u5168\u6e05\u695a\u81ea\u5df1\u5728\u8208\u596e\u4ec0\u9ebd\u6216\u7dca\u5f35\u4ec0\u9ebd\uff1a\u6211\u5011\u7a76\u7adf\u77e5\u9053\u4e86\u591a\u5c11\u4eba\u985e\u751f\u547d\u7684\u79d8\u5bc6\uff1f\u76ee\u524d\u7684\u767c\u73fe\u5c0d\u4eba\u985e\u793e\u6703\u7684\u672a\u4f86\u5230\u5e95\u6703\u7523\u751f\u600e\u6a23\u7684\u5f71\u97ff\uff1f\u672c\u6587\u6839\u64da\u300a\u81ea\u7136\u300b\u548c\u300a\u79d1\u5b78\u300b\u96dc\u8a8c\u516c\u4f48\u7684\u7814\u7a76\u5831\u544a\uff0c\u4ee5\u53ca\u76f8\u95dc\u7684\u5c08\u5bb6\u8a55\u8ad6\u548c\u5206\u6790\u6587\u7ae0\u9032\u884c\u7de8\u8b6f\u7d9c\u8ff0\uff0c\u5411\u4e2d\u6587\u4e16\u754c\u7684\u8b80\u8005\u4ecb\u7d39\u9019\u9805\u7814\u7a76\u7684\u9032\u5c55\u548c\u610f\u7fa9\u3002<\/p>\n

<\/p>\n

\"2\u670816\u65e5\u51fa\u7248\u7684\u300a\u79d1\u5b78\u300b\u96dc\u8a8c\"

2\u670816\u65e5\u51fa\u7248\u7684\u300a\u79d1\u5b78\u300b\u96dc\u8a8c<\/p><\/div>\n

\u4e00\uff0e\u4ec0\u9ebd\u662f”\u4eba\u985e\u57fa\u56e0\u7d44\u5e8f\u5217”\uff1f<\/p>\n

\u6211\u5011\u77e5\u9053\uff0c\u751f\u7269\u662f\u7531\u7d30\u80de\u7d44\u7e54\u69cb\u6210\u7684\uff0c\u7d30\u80de\u7684\u5404\u7a2e\u65b0\u9673\u4ee3\u8b1d\u4f5c\u7528\u986f\u73fe\u7232\u751f\u7269\u6a5f\u9ad4\u7684\u767c\u80b2\u3001\u6210\u9577\u3001\u75c5\u8b8a\u3001\u8870\u8001\u548c\u6b7b\u4ea1\u3002\u6bcf\u4e00\u500b\u9ad8\u7b49\u751f\u7269\u7684\u7d30\u80de\u90fd\u6709\u7d30\u80de\u6838\uff0c\u5176\u4e2d\u7684\u67d3\u8272\u9ad4\u5c31\u5132\u5b58\u4e86\u6574\u500b\u751f\u7269\u7684”\u751f\u547d\u85cd\u5716”\uff0c\u5305\u62ec\u5176\u69cb\u9020\u548c\u4e00\u5207\u81ea\u7136\u8b8a\u5316\u3002\u4eba\u985e\u670923\u5c0d46\u689d\u5206\u5225\u4f86\u81ea\u7236\u6bcd\u96d9\u89aa\u7684\u67d3\u8272\u9ad4\u3002\u67d3\u8272\u9ad4\u7d50\u69cb\u4e3b\u8981\u7531\u86cb\u767d\u8cea\u548cDNA\u5206\u5b50\u7d44\u6210\u3002\u57fa\u56e0\u5247\u662fDNA\u5206\u5b50\u7684\u7247\u65b7\uff0c\u662f\u542b\u6709\u7279\u5b9a\u907a\u50b3\u4fe1\u606f\u7684\u4e00\u6bb5\u5e8f\u5217\u7d50\u69cb\uff0c\u4e5f\u662f\u907a\u50b3\u7269\u8cea\u7684\u6700\u5c0f\u529f\u80fd\u55ae\u4f4d\u3002\u57fa\u56e0\u5177\u6709\u7de8\u78bc\u6307\u4ee4\u7684\u529f\u80fd\uff0c\u7528\u4f86\u6307\u793a\u63a7\u5236\u86cb\u767d\u8cea\u7684\u5408\u6210\u8207\u8907\u88fd\u904e\u7a0b\uff0c\u4e5f\u6c7a\u5b9a\u4e86\u4eba\u985e\u7684\u751f\u7269\u7a2e\u6027\u7279\u5fb5\u3002\u7c21\u55ae\u5730\u8aaa\uff0c\u5c31\u662f\u57fa\u56e0\u6c7a\u5b9a\u86cb\u767d\u8cea\u7684\u5408\u6210\uff0c\u86cb\u767d\u8cea\u6c7a\u5b9a\u4ee3\u8b1d\u4f5c\u7528\uff0c\u4ee3\u8b1d\u4f5c\u7528\u6c7a\u5b9a\u5404\u7a2e\u6027\u72c0<\/p>\n

\"\u986f\u5fae\u93e1\u4e0b\u770b\u4eba\u985e\u67d3\u8272\u9ad4\"

\u986f\u5fae\u93e1\u4e0b\u770b\u4eba\u985e\u67d3\u8272\u9ad4<\/p><\/div>\n

\u90a3\u9ebd\uff0cDNA\u8207\u57fa\u56e0\u53c8\u662f\u4ec0\u9ebd\u95dc\u4fc2\u5462\uff1fDNA\u5206\u5b50\u7684\u55ae\u5143\u6210\u4efd\u4e26\u4e0d\u8907\u96dc\uff0c\u5b83\u662f\u7531\u56db\u7a2e\u6838\u82f7\u9178\u5206\u5b50A\u3001T\u3001C\u3001G\u69cb\u6210\uff08\u5b83\u5011\u4e5f\u88ab\u7a31\u7232\u907a\u50b3\u7de8\u78bc\u7684\u5b57\u6bcd\uff09\uff0c\u800c\u5728DNA\u5206\u5b50\u7684\u96d9\u87ba\u65cb\u93c8\u4e0a\u9762\uff0cA\u548cT\uff0cC\u548cG\u7e3d\u662f\u5169\u5169\u914d\u5c0d\u7684\uff0c\u9019\u7a31\u7232\u583f\u57fa\u5c0d\uff08base pair\uff09\u3002\u8907\u96dc\u800c\u91cd\u8981\u7684\u662fDNA\u5206\u5b50\u4e2d\u583f\u57fa\u5c0d\u7684\u6392\u5217\u9806\u5e8f\u3002\u9019\u4e9b\u5de8\u9577\u7684\u3001\u6392\u5217\u898f\u5247\u591a\u8b8a\u7684\u583f\u57fa\u5c0d\u5e8f\u5217\u4e2d\uff0c\u53ea\u6709\u4e00\u4e9b\u7247\u65b7\u624d\u662f\u57fa\u56e0\u3002\u6309\u7167\u529f\u80fd\u7684\u4e0d\u540c\uff0c\u57fa\u56e0\u5206\u4ee5\u7232\u4e09\u985e\uff1a\u7b2c\u4e00\u985e\u662f\u7de8\u78bc\u86cb\u767d\u8cea\u7684\u57fa\u56e0\uff0c\u5b83\u5177\u6709\u8f49\u9304\u548c\u7ffb\u8b6f\u529f\u80fd\uff1b\u7b2c\u4e8c\u985e\u53ea\u6709\u8f49\u9304\u529f\u80fd\u800c\u6c92\u6709\u7ffb\u8b6f\u529f\u80fd\uff0c\u5305\u62ectRNA\u57fa\u56e0\u548crRNA\u57fa\u56e0\uff1b\u7b2c\u4e09\u985e\u662f\u4e0d\u8f49\u9304\u7684\u57fa\u56e0\uff0c\u5b83\u5c0d\u57fa\u56e0\u8868\u9054\u8d77\u8abf\u7bc0\u63a7\u5236\u4f5c\u7528\uff0c\u5305\u62ec\u5553\u52d5\u57fa\u56e0\u548c\u64cd\u7e31\u57fa\u56e0\uff0c\u6709\u6642\u88ab\u7d71\u7a31\u7232\u63a7\u5236\u57fa\u56e0\u3002<\/p>\n

\u6240\u8b02\u7834\u8b6f\u4eba\u985e\u57fa\u56e0\u7d44\u5e8f\u5217\uff0c\u5c31\u662f\u5206\u8fa8\u548c\u78ba\u5b9a\u4eba\u985e\u5168\u90e823\u5c0d\u67d3\u8272\u9ad4\u4e2dDNA\u5206\u5b50\u7684\u6240\u6709\uff08\u5927\u7d0432\u5104\u5c0d\uff09\u583f\u57fa\u5c0d\u7684\u5b8c\u6574\u5e8f\u5217\u7d50\u69cb\uff0c\u4ee5\u53ca\u5728\u9019\u5e8f\u5217\u4e2d\u7684\u57fa\u56e0\u53ca\u5176\u985e\u5225\u3002\u8a2d\u60f3\u4e00\u4e0b\uff0c\u5982\u679c\u8aaa\u4eba\u985e\u57fa\u56e0\u7d44\u662f\u4e00\u90e8”\u751f\u547d\u7684\u5929\u66f8”\uff0c\u90a3\u9ebd\u9019\u672c\u66f8\u662f\u5982\u6b64\u5de8\u5927\u800c\u6df1\u5967\uff0c\u5b83\u75314\u7a2e32\u5104\u5c0d\u5b57\u6bcd\u69cb\u6210\uff0c\u5176\u4e2d\u7684\u6bcf\u500b\u53e5\u5b50\u90fd\u6975\u5176\u5197\u9577\uff0c\u800c\u53e5\u5b50\u7576\u4e2d\u6c92\u6709\u4efb\u4f55\u6a19\u9ede\u7b26\u865f\u5206\u5272\u3002\u57fa\u56e0\u662f\u9019\u4e9b\u9577\u53e5\u5b50\u4e2d\u7684\u4e00\u500b\u500b\u7368\u7acb\u7247\u6bb5\uff0c\u5176\u9577\u5ea6\u5f9e\u5927\u7d041\u5343\u523010\u842c\u5c0d\u5b57\u6bcd\uff08\u583f\u57fa\u5c0d\uff09\u4e0d\u7b49\u3002\u53ef\u60f3\u800c\u77e5\uff0c\u8981\u78ba\u5b9a\u8fa8\u8b58\u9019\u672c\u5929\u66f8\u4e2d\u7684\u6240\u6709\u5b57\u6bcd\u7684\u6392\u5217\u9806\u5e8f\u662f\u4f55\u7b49\u8271\u5de8\u7684\u5de5\u4f5c\u3002<\/p>\n

 <\/p>\n

\"DNA\u7684\u7d50\u69cb\u7167\u7247\"

DNA\u7684\u7d50\u69cb\u7167\u7247<\/p><\/div>\n

\u4e8c\uff0e\u6211\u5011\u767c\u73fe\u4e86\u4ec0\u9ebd\uff1f<\/p>\n

\u76ee\u524d\u767c\u8868\u7684\u57fa\u56e0\u7d44\u5716\u8b5c\u8986\u84cb\u4e86\u4eba\u985e\u57fa\u56e0\u7d44\u768495\uff05\uff0c\u5e73\u5747\u6e2c\u5e8f\u7cbe\u78ba\u7a0b\u5ea6\u723299.96\uff05\u3002\u800c\u57fa\u56e0\u7d44\u5e8f\u5217\u4e2d\u6bcf\u500b\u67d3\u8272\u9ad4\u7684\u5716\u8b5c\u90fd\u662f\u5982\u6b64\u5de8\u5927\uff0c\u4ee5\u81f3\u65bc\u6211\u5011\u7121\u6cd5\u5728\u6b64\u76f4\u63a5\u986f\u793a\uff0c\u6709\u8208\u8da3\u7684\u8b80\u8005\u53ef\u4ee5\u5230\u4e0b\u5217\u93c8\u7d50\u4e2d\u4e0b\u8f09\u67e5\u770bPDF\u683c\u5f0f\u7684\u5716\u8b5c\u3002<\/p>\n\n\n\n\n\n\n\n
\u300a\u81ea\u7136\u300b\u96dc\u8a8c\u63d0\u4f9b\u7684\u6240\u6709\u67d3\u8272\u9ad4\uff08chromosomes\uff09\u5716\u8b5c\uff08\u4e0b\u8f09PDF\u683c\u5f0f\uff09<\/td>\n<\/tr>\n
\u57161\u00a0PDF 1 (3265K)<\/a>\uff1a\u67d3\u8272\u9ad4\u00a01 – 3 and 20 – 22<\/td>\n<\/tr>\n
\u57162\u00a0PDF 2 (3049K)<\/a>\uff1a\u67d3\u8272\u9ad4\u00a04 – 6 and 17 – 19<\/td>\n<\/tr>\n
\u57163\u00a0PDF 3 (2287K)<\/a>\uff1a\u67d3\u8272\u9ad4\u00a07 – 9 and 20 – 22<\/td>\n<\/tr>\n
\u57163\u00a0PDF 4 (2737K)<\/a>\uff1a\u67d3\u8272\u9ad4\u00a010 – 11, X, Y, and 12 – 13<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n\n
\u300a\u79d1\u5b78\u300b\u96dc\u8a8c\u63d0\u4f9b\u7684\u6240\u6709\u67d3\u8272\u9ad4\uff08chromosomes\uff09\u5716\u8b5c\uff08\u4e0b\u8f09PDF\u683c\u5f0f\uff09<\/td>\n<\/tr>\n
Chromosome 1<\/a>(889K0)<\/td>\nChromosome 9<\/a>
\n(555K)<\/td>\n		Chromosome 17<\/a>(611K)<\/td>\n<\/tr>\n
Chromosome 2<\/a>(788K)<\/td>\nChromosome 10<\/a>(557K)<\/td>\nChromosome 18<\/a>(412K)<\/td>\n<\/tr>\n
Chromosome 3<\/a>(713K)<\/td>\nChromosome 11<\/a>(672K)<\/td>\nChromosome 19<\/a>(620K)<\/td>\n<\/tr>\n
Chromosome 4<\/a>(598K)<\/td>\nChromosome 12<\/a>(648K)<\/td>\nChromosome 20<\/a>(460K)<\/td>\n<\/tr>\n
Chromosome 5<\/a>(647K)<\/td>\nChromosome 13<\/a>(444K)<\/td>\nChromosome 21<\/a>(354K)<\/td>\n<\/tr>\n
Chromosome 6<\/a>(659K)<\/td>\nChromosome 14<\/a>(499K)<\/td>\nChromosome 22<\/a>(440K)<\/td>\n<\/tr>\n
Chromosome 7<\/a>(608K)<\/td>\nChromosome 15<\/a>(485K)<\/td>\nChromosome X<\/a>(540K)<\/td>\n<\/tr>\n
Chromosome 8<\/a>(547K)<\/td>\nChromosome 16<\/a>(504K)<\/td>\nChromosome Y<\/a>(296K)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5c0d\u65bc\u4e00\u822c\u8b80\u8005\u800c\u8a00\uff0c\u57fa\u56e0\u7d44\u5e8f\u5217\u5716\u8b5c\u5e7e\u4e4e\u662f\u7121\u6cd5\u8b80\u89e3\u7684”\u5929\u66f8”\u3002\u90a3\u9ebd\uff0c\u79d1\u5b78\u5bb6\u5f9e\u4e2d\u767c\u73fe\u4e86\u4ec0\u9ebd\u5462\uff1f<\/p>\n

1\uff0e\u4eba\u985e\u57fa\u56e0\u7684\u6578\u91cf\u7a00\u5c11<\/p>\n

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2\uff0e\u4eba\u985e\u57fa\u56e0\u7684\u6563\u6f2b\u5206\u4f48\u3001\u788e\u7247\u5316\u548c\u91cd\u5fa9<\/p>\n

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2\u865f\u548c22\u865f\u67d3\u8272\u9ad4\u4e2d\u7684\u5169\u500b\u5340\u6bb5\uff0810\u842c\u583f\u57fa\u5c0d\uff09\u3002\u5176\u4e2d\u7684\u7d05\u8272\u689d\u584a\u6563\u4f48\u8457\u91cd\u5fa9\u5e8f\u5217\uff0c
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 <\/p>\n

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\u540c\u6642\uff0c\u4eba\u985e\u5bc4\u751f\u6027DNA\u7684\u91cd\u5fa9\u5e8f\u5217\u4e2d\uff0c\u5f88\u5c11\u6709\u57fa\u56e0\u7a81\u8b8a\u6240\u8981\u6c42\u7684”\u91cd\u65b0\u63d2\u5165”\uff08reinserting\uff09\u7684\u8ff9\u8c61\uff0c\u591a\u534a\u662f\u5782\u8001\u4e0d\u8b8a\uff0c\u9019\u53ef\u80fd\u662f\u6f2b\u9577\u9032\u5316\u6240\u7559\u4e0b\u7684\u907a\u8ff9\uff0c\u7232\u7814\u7a76\u4eba\u985e\u7684\u57fa\u56e0\u9032\u5316\u63d0\u4f9b\u4e86\u7dda\u7d22\u3002<\/p>\n

3\uff0e\u4eba\u985e\u57fa\u56e0\u8207\u7a2e\u65cf\u548c\u6027\u5225<\/p>\n

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\"Y\u6bd4X\u67d3\u8272\u9ad4\u5177\u6709\u66f4\u9ad8\u7684\u7f6e\u63db\u5f8b\uff08substitution

Y\u6bd4X\u67d3\u8272\u9ad4\u5177\u6709\u66f4\u9ad8\u7684\u7f6e\u63db\u5f8b\uff08substitution rate\uff09\uff0c
\u5716\u8868\u7531\u300a\u81ea\u7136\u300b\u96dc\u8a8c\u6388\u6b0a\u4f7f\u7528\u3002<\/p><\/div>\n

 <\/p>\n

\u901a\u904e\u5206\u6790Y\u67d3\u8272\u9ad4\u4e0a300\u842c\u500b\u91cd\u5fa9\u55ae\u5143\uff0c\u6aa2\u6e2c\u91cd\u5fa9\u6563\u4f48\u7684\u5f62\u5f0f\uff0c\u7814\u7a76\u8005\u4f30\u8a08\u4e86X\u548cY\u67d3\u8272\u9ad4\u7684\u76f8\u5c0d\u7a81\u8b8a\u7387\uff0c\u767c\u73fe\u7537\u6027\u548c\u5973\u6027\u7684\u7a81\u8b8a\u6bd4\u4f8b\u72322\u6bd41\u3002\u9019\u8868\u660e\uff0c\u4eba\u985e\u9032\u5316\u7684\u4e3b\u8981\u56e0\u7d20\u662f\u5b9a\u7fa9\u7537\u6027\u6027\u5225\u7684\u67d3\u8272\u9ad4Y\uff0c\u5373\u7537\u6027\u5728\u4eba\u985e\u9032\u5316\u904e\u7a0b\u4e2d\u626e\u6f14\u4e86\u81f3\u95dc\u91cd\u8981\u7684\u89d2\u8272\u3002<\/p>\n

4\uff0e\u57fa\u56e0\u8207\u75be\u75c5<\/p>\n

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HGP\u7684\u7814\u7a76\u7684\u767c\u73fe\u4e861778\u500b\u75be\u75c5\u57fa\u56e0\uff0c\u76f8\u7576\u65bc\u672a\u77e5\u75be\u75c5\u57fa\u56e0\u768440%\uff0c\u5176\u4e2d\u81f3\u5c11\u670930\u7a2e\u75be\u75c5\u57fa\u56e0\u5df2\u7d93\u901a\u904e\u514b\u9686\u5b9a\u4f4d\u6cd5\u88ab\u5b8c\u5168\u5b9a\u4f4d\u3002\u572823\u5c0d\u67d3\u8272\u9ad4\u4e2d\uff0c\u81f3\u5c11\u67093\u7d44\u57fa\u56e0\u548c\u907a\u50b3\u6027\u75be\u75c5\u9ad8\u5ea6\u76f8\u95dc\uff0c\u7b2c1\u865f\u67d3\u8272\u9ad4\u4e2d\u6709\u8207\u963f\u8332\u6d77\u9ed8\u75c7\u76f8\u95dc\u7684\u57fa\u56e0\uff0c\u7b2c6\u865f\u67d3\u8272\u9ad4\u7684\u57fa\u56e0\u8207\u4eba\u985e\u667a\u6167\u6709\u95dc\uff0cX\u67d3\u8272\u9ad4\u66f4\u662f\u5e36\u6709\u8a31\u591a\u75be\u75c5\u57fa\u56e0\uff0c\u548c\u6578\u5341\u7a2e\u75be\u75c5\u6709\u806f\u7e6b\u3002\u7814\u7a76\u8005\u8a8d\u7232\uff0c\u764c\u75c7\u5be6\u969b\u4e0a\u4e5f\u662f\u4e00\u7a2e\u57fa\u56e0\u75be\u75c5\u3002<\/p>\n

 <\/p>\n

\"\u4eba\u8207\u4eba\u4e4b\u9593\u7684\u5dee\u7570\u8b8a\u5316\u4e3b\u8981\u4f86\u6e90\u65bcSNPS\uff0c

\u4eba\u8207\u4eba\u4e4b\u9593\u7684\u5dee\u7570\u8b8a\u5316\u4e3b\u8981\u4f86\u6e90\u65bcSNPS\uff0c
\u5716\u7247\u7531\u300a\u81ea\u7136\u300b\u96dc\u8a8c\u6388\u6b0a\u4f7f\u7528\u3002<\/p><\/div>\n

5\uff0e\u57fa\u56e0\u8207\u86cb\u767d\u8cea\uff1a\u8907\u96dc\u7684\u6a5f\u7406<\/p>\n

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\u4f5c\u7232HGP\u76f8\u95dc\u7814\u7a76\u7684\u4e00\u90e8\u5206\uff0cRossella Tupler\uff0cGiovanni Perini\u548cMichael R. Green\u5728\u672c\u671f\u300a\u81ea\u7136\u300b\u4e0a\u767c\u8868\u4e86\u4ed6\u5011\u95dc\u65bc\u57fa\u56e0\u8868\u9054\u7684\u7814\u7a76\u7d50\u679c\u3002\u4ed6\u5011\u8457\u91cd\u7814\u7a76\u4e86\u63a7\u5236\u57fa\u56e0\u8868\u9054\u7684\u4e09\u500b\u968e\u6bb5\uff1a\u5f9e\u57fa\u56e0\u5230mRNA\u7684\u8f49\u9304\uff1bmRNA\u7684\u521d\u6b65\u63a5\u5408\uff0c\u4ee5\u53ca\u591a\u805aA\u5c3e\u7684\u52a0\u5165\u3002\u4ed6\u5011\u767c\u73fe\uff0c\u96d6\u7136\u4eba\u985e\u7684\u8a31\u591a\u57fa\u56e0\u5e8f\u5217\u8207\u9175\u6bcd\u548c\u679c\u8805\u7684\u5e8f\u5217\u5341\u5206\u76f8\u4f3c\uff0c\u4f46\u4eba\u985e\u6709\u66f4\u591a\u7684\u7279\u6b8a\u8f49\u9304\u56e0\u6578\u76f8\u95dc\u5e8f\u5217TFIID\uff0c\u9019\u610f\u5473\u8457\u4eba\u985eTFIID\u5177\u6709\u66f4\u8c50\u5bcc\u7684\u6f5b\u5728\u591a\u6a23\u6027\u3002\u4ed6\u5011\u9084\u767c\u73fe\uff0c\u5728\u8f49\u9304\u555f\u52d5\u5291\u7684\u904e\u7a0b\u4e2d\uff0c\u67092000\u591a\u500b\u57fa\u56e0\u7de8\u78bc\u4e86\u9019\u4e9b\u86cb\u767d\u3002\u5728\u5c0b\u627e\u8207mRNA\u63a5\u5408\u6709\u95dc\u7684\u57fa\u56e0\u6642\u4e5f\u767c\u73fe\u4e86\u76f8\u540c\u7684\u7d50\u679c\u3002\u5728\u7814\u7a76\u591a\u805aA\u5c3e\u52a0\u5165\u7684\u6709\u95dc\u57fa\u56e0\u6642\uff0c\u4ed6\u5011\u610f\u5916\u5730\u767c\u73fe\u4e86\u65b0\u7684\u57fa\u56e0\uff0c\u9019\u8868\u660e\u4eba\u985e\u7684\u57fa\u56e0\u8868\u9054\u6a5f\u5236\u6975\u5176\u8907\u96dc\uff0c\u8a31\u591a\u65b0\u57fa\u56e0\u53ef\u80fd\u8868\u9054\u4e86\u5927\u86cb\u767d\u8907\u5408\u9ad4\u7684\u4e9e\u55ae\u4f4d\uff0c\u9700\u8981\u9032\u884c\u9032\u4e00\u6b65\u7684\u7814\u7a76\u4f86\u7406\u89e3\u5176\u529f\u80fd\u3002\u7531\u6b64\uff0c\u672a\u4f86\u7684\u751f\u547d\u79d1\u5b78\u7814\u7a76\u5c07\u4ee5\u4eba\u9ad4\u7684\u86cb\u767d\u8cea\u5f62\u6210\u7232\u4e3b\u8981\u76ee\u6a19\u3002<\/p>\n

\u4e09\uff0e\u4eba\u985e\u57fa\u56e0\u7d44\u5716\u8b5c\u7684\u610f\u7fa9<\/p>\n

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\u300a\u81ea\u7136\u300b\u96dc\u8a8c\u7684\u9867\u554f\u7de8\u8f2fPhilip Ball\u4ee5\u9019\u6a23\u4e00\u500b\u60c5\u666f\u4f86\u985e\u6bd4\u76ee\u524d\u4eba\u985e\u57fa\u56e0\u7d44\u5e8f\u5217\uff08\u57fa\u672c\uff09\u5b8c\u6210\u7684\u610f\u7fa9\u3002\u6211\u5011”\u751f\u547d\u7684\u5929\u66f8”\u7684\u72c0\u6cc1\u5f88\u50cf\u662f\u90a3\u90e8\u53e4\u4ee3\u7684\u795e\u79d8\u66f8\u7a3f\uff0c\u5373\u4fbf\u4f60\u53ef\u4ee5\u8fa8\u8b58\u6bcf\u4e00\u500b\u5b57\u6bcd\u4e26\u78ba\u5b9a\u6240\u6709\u5b57\u6bcd\u7684\u6392\u5217\u9806\u5e8f\uff0c\u4f60\u4ecd\u7136\u9084\u7121\u6cd5\u771f\u6b63\u8b80\u61c2\u5b83\u3002\u5c0d\u751f\u7269\u5b78\u7684\u771f\u6b63\u9769\u547d\uff0c\u76ee\u524d\u7684\u7814\u7a76\u6210\u679c\u800c\u8a00\u50c5\u50c5\u662f\u4e00\u500b\u958b\u59cb\uff0c\u66f4\u7232\u91cd\u8981\u6216\u8a31\u4e0d\u662f\u5c0d\u57fa\u56e0\u7d44\u5e8f\u5217\u7684\u78ba\u5b9a\uff0c\u800c\u662f\u767c\u73fe\u5728\u9019\u4e9b\u5e8f\u5217\u4e2d\u57fa\u56e0\u6d3b\u52d5\u548c\u76f8\u4e92\u4f5c\u7528\u7684\u6a21\u578b\u3002\u7528Philip Ball\u7684\u8a71\u4f86\u8aaa\uff0c”\u57fa\u56e0\u7d44\u6c92\u6709\u654d\u4e8b\u800c\u53ea\u662f\u4e00\u90e8\u8a5e\u5178\uff0c\u6240\u6709\u7684\u6545\u4e8b\u662f\u5728\u8a5e\u8207\u8a5e\u7684\u76f8\u4e92\u52d5\u614b\u95dc\u806f\u4e2d\u624d\u80fd\u5c55\u958b\uff0c\u6b63\u50cf\u7d30\u80de\u6240\u5c55\u958b\u7684\u6545\u4e8b\u4e00\u6a23”\u3002<\/p>\n

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* \u585e\u840a\u62c9\u516c\u53f8\u7684\u6838\u5fc3\u5206\u6790\u65b9\u6cd5\u88ab\u7a31\u7232”\u9730\u5f48\u6cd5”\uff0cHGP\u5247\u63a1\u7528\u4e86”\u514b\u9686\u6cd5”\uff0c\u5169\u500b\u7814\u7a76\u7d44\u5c07\u8cc7\u6599\u9032\u884c\u7684\u5c0d\u6bd4\u4ee5\u53ca\u4eba\u985e\u57fa\u56e0\u7d44\u5de5\u7a0b\u7684\u79d1\u5b78\u5bb6\u3001\u300a\u79d1\u5b78\u300b\u548c\u300a\u81ea\u7136\u300b\u96dc\u8a8c\u9ad8\u7d1a\u6307\u5c0e\u7de8\u8f2f\u7684\u8a55\u4f30\u8868\u660e\uff0c\u585e\u840a\u62c9\u516c\u53f8\u7684\u57fa\u56e0\u7d44\u5206\u6790\u8207\u4eba\u985e\u57fa\u56e0\u7d44\u8a08\u5283\u7684\u5206\u6790\u7d50\u679c\u96d6\u7136\u5b58\u5728\u4e00\u4e9b\u5dee\u7570\uff0c\u4f46\u5927\u90e8\u5206\u5730\u65b9\u90fd\u6709\u6975\u9ad8\u7684\u543b\u5408\u5ea6\u3002<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u30102001.02.23 \u00a0\u53f2\u5b63\u937e\u7de8\u8b6f\u3011 \u3000”\u4eba\u985e\u57fa\u56e0\u7d44\u5e8f\u5217”\u7684\u7834\u8b6f\u662f\u79d1\u5b78\u53f2\u4e0a\u7684\u91cc\u7a0b\u7891\uff0c […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,22],"tags":[],"class_list":["post-917","post","type-post","status-publish","format-standard","hentry","category-body","category-geneengineering"],"_links":{"self":[{"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=\/wp\/v2\/posts\/917","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=917"}],"version-history":[{"count":0,"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=\/wp\/v2\/posts\/917\/revisions"}],"wp:attachment":[{"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=917"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sex.ncu.edu.tw\/blognews\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}